Imaging Specialist

Requisition # 2024-18565
Date Posted 5 months ago(2/20/2024 9:33 AM)
Princeton Neuroscience Inst
Research and Laboratory
Job Type
Name of Lab
Seung Lab


Petascale EM Imaging Specialist


The Princeton Neuroscience Institute is searching for an accomplished scientist to lead acquisitions of petascale image datasets via volume electron microscopy (EM). The Institute is the only site in the world hosting beam deflection transmission EM and multibeam scanning EM instruments, both of which have sufficient throughput for petascale connectomics. The Institute leads the FlyWire Consortium, which in 2023 released the first connectome of an adult brain, that of the fruit fly Drosophila melanogaster. The Institute is a key performer in the NIH BRAIN CONNECTS program, which aims to scale connectomics up to the whole mouse brain.




Key Responsibilities:


  • Preparation of EM sample by fixation, staining, and embedding
  • MicroCT imaging of EM sample
  • Cutting and collecting series of ultrathin sections
  • Volume imaging with transmission EM and multibeam scanning EM
  • Maintenance of microscopes and other instruments
  • Training collaborators at PNI on EM procedures


Essential Qualifications:

  • PhD degree in Neuroscience, Physics, Electrical Engineering or other related field.
  • At least 4 years hands-on experience in an EM laboratory
  • Ability to organize and execute several projects in parallel
  • Ability to work collaboratively in a team as well as independently on a wide variety of research projects
  • Excellent communication skills
  • Detail-oriented, focused, and highly motivated


Preferred Qualifications:  


  • Experience with serial section EM
  • Histology
  • Viral and immuno labeling
  • Stereotaxic surgery 
  • Image analysis software and systems (e.g. FIJI/ImageJ, EyeWire)
  • Light microscopy
  • Experience with tilt series EM tomography



Princeton University is an Equal Opportunity/Affirmative Action Employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability status, protected veteran status, or any other characteristic protected by law. KNOW YOUR RIGHTS

Standard Weekly Hours


Eligible for Overtime


Benefits Eligible


Probationary Period

180 days

Essential Services Personnel (see policy for detail)


Estimated Appointment End Date


Physical Capacity Exam Required


Valid Driver's License Required




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